Predisposition to acne

In our DNA skin test we can show whether you have an (increased)  predisposition for acne. There are several genes that influence this.

What is acne?

What we normally call acne is officially called acne vulgaris. It is one of the most common skin complaints and affects almost 10% of the world population. It arises, for example, during puberty, due to hormonal overstimulation of the sebaceous glands in the face, back and chest.

The bacterium propionibacterium acnes

The hormonal stimulation causes enlargement of the sebaceous glands and increased sebum production. When sebum accumulates in the glands, the growth of the bacterium Propionibacterium acnes is stimulated, which feeds on sebum. The bacteria is naturally present on the skin, but when acne develops, these bacteria colonies grow extra hard and form inflammatory (inflamed) and non-inflammatory (non-inflamed) acne lesions (injury).

What causes acne?

In general, pimples during puberty are caused by changes in hormone levels and disappear when the hormones stabilize. Unfortunately, this isn’t the case for everyone, and some people have acne breakouts into adulthood, sometimes all their lives.

Causes for this could be stress-related disturbances in the hormonal balance of the body, lifestyle and food choices or medical or drug use, but there can also be a genetic cause. Understanding the cause of ongoing acne can also provide insight into what might be done to improve it.

What does your genetic profile say

In our DNA skin test we will investigate your genetic profile. We check whether you may have an (increased) predisposition to acne. If so, you may have frequent breakouts and a higher risk of long-term acne. If you suffer from persistent acne, a GP and/or dermatologist can advise on what may be triggering or making it worse, as well as treatments and lifestyle advice.

In case of increased acne predisposition, it may be important that you use skin care products and make-up that are suitable for acne-prone skin. For example, it is wise to choose products that are not oil-based and hypoallergenic. Be aware that you are prone to acne, and if you notice that your skin reacts or looks different, you may want to switch to customized products.

We look at the following genes:

  • rs7531806 : SELL – Associated with acne severity
  • rs747650 : DDB2 – Associated with acne risk and severity
  • rs1060573 : DDB2 – Associated with acne risk and severity
  • rs478304 : OVOL1 – Associated with acne risk
  • rs38055 : FST – Affects the risk of acne
  • rs1159268 : TGFB2 – Associated with acne risk

Buy your skin report now

In our DNA report that focuses on the skin (Dermagenomics) you will receive information about the following components:

  • Acne: Information based on your genetic profile about your predisposition to acne.
  • UV sensitivity: Information based on your genetic profile about skin aging, pigmentation spots, wrinkle formation, drooping cheeks and advice.
  • Intrinsic skin aging: Information based on your genetic profile about the risk of crow’s feet, drooping cheeks, smile lines, drooping eyelids and advice.

Nutrigenomics

Provides insight into your genetic predisposition with regard to various metabolic processes in the body. A genetic profile can help make the right choices to meet the body’s daily nutrient needs.

A genetic profile can help make the right choices to meet the body’s daily nutrient needs.

Healthy weight

Macronutrient Balance

Micronutrients

Salt sensitivity

Do you know?